What Is Viagra Online?
Sildenafil citrate – Viagra was firstly synthesized in 1989 by Piter Dann, Albert Wood and other scientists of Pzizer, a pharmaceutical company. The trials were conducted in the research and development centre in England. Such names as Andrew Bell, David Brown, Nicholas Terret are also important in Viagra creation because these people helped to identify that chemical compounds referred to pyrazolopyrimidinone group. This pyrazolopyrimidinone group is considered to be effective in cardiac disorders treatment such as stenocardia. Terret obtain British patent for sildenafil in 1991 as cardiac remedy and some experts consider it to be Viagra ancestor.
Initial Aim of Viagra
Viagra was initially studied for use at arterial hypertension (the raised blood pressure) and stenocardia (coronary heart disease symptom) prevention. During the first phase of clinical tests under the leadership of Jan Osterloh, it was taped that drug has insignificant influence on stenocardia, but it can cause erection improvement.
After the 2nd phase of trials, I didn’t confirm promising results in sildenafil treatment of stenocardia, Pfizer representatives decided to continue researches of substance in erectile dysfunction treatment. Drug was patented in 1996 and approved for use in erectile dysfunction treatment by Food and Drug Administration on March 27, 1998. Viagra became the first peroral agent for erectile dysfunction treatment approved in the United States, been available for sale in the USA the same year. Viagra sales still exceed the income in 1 billion a year.
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Key Events of Viagra
- 1989
Pfizer scientists synthesized sildenafil citrate determing it as the method of stenocardia and arterial hypertension treatment. - 1991
Research and development centre representatives claimed that Viagra became effective at erectile dysfunction treatment. - 1992
Being a stenocardia treatment one of the most significant side effects was defined – erection. - 1993
Trials of Viagra as the effective method of erectile dysfunction treatment were conducted in Bristol, England. - 1994
The second phase of trials showed the influence of this medication on erection once a day. - 1994-1997
Collectively 20 clinical trials were carried out with usage of 4500 men. The common amount of examinees is 4500. they proved that Viagra is considered to be effective and safe. - 1997
Pfizer handed documents in FDA. - 1998
FDA approves Viagra as erectile dysfunction treatment.
Category: General Issues
Tags: Men’s Health, sexual dysfunction, Viagra 50 mg